South Carolina villa rentals

Select from 3,074 villa rentals around South Carolina. Take the family on an adventure to Beaufort or explore other popular cities like North Myrtle Beach and Charleston. Wherever you’re headed, we’ve got spacious properties in stunning and exclusive locations.

Our filters make it a breeze to find a villa rental in South Carolina that suits your budget. Narrow your search by entering your maximum nightly or total price. Consider your timing as well. Prices can vary based on peak seasons, major holidays or special events. You may find lower rates in off-peak times.

Follow the lead of others and go in March. That’s the most popular month to book a villa rental in South Carolina. However, you’re the boss of your own adventure, so consider what’s most important to you and the weather conditions you prefer before clicking “book.”

Wake up and wind down with impressive views when you stay in one of our welcoming villa rentals in South Carolina. Scroll through the options and make use of our filter tool to customize your search by location and the vistas you want to gaze at when you’re there. Many of our villas come with outdoor areas like private gardens, balconies or terraces, allowing you to appreciate your surroundings even more.

Check out our selection of luxury villa rentals in South Carolina and prepare to live it up like a celebrity on your next getaway. We have high-end properties in cities like Beaufort and Charleston that feature premium amenities such as plush furnishings, gourmet kitchens and advanced in-home entertainment systems. For even more indulgence, look for villas with a private pool or spa facilities.

Head out and experience everything South Carolina has to offer from the comfort of your villa rental. We recommend doing a bit of research on what you’d like to do and see, so you can plan the perfect trip.

Booking a villa rental with Vrbo means you’ll have the whole place for your exclusive use — your own private space, without any interruptions or distractions from other people. Not only that, our flexible payment and cancellation policies give you the freedom to alter your plans if required. Plus, with our One Key™ rewards platform, you can earn and redeem OneKeyCash™* on eligible bookings on Vrbo, Expedia and Hotels.com. *OneKeyCash disclaimer - OneKeyCash is not redeemable for cash and can only be used on Vrbo, Expedia and Hotels.com.