Panama City house rentals

We found 1,996 house rentals — enter your dates for availability

  • Peace of mind
    Our Book with Confidence guarantee gives you 24/7 support
  • All the privacy of home
    Enjoy full kitchens, laundry, pools, yards and more
  • More for less
    More space, more privacy, more amenities — more value
  • A place for everyone
    We stand for diversity, inclusion and families everywhere.
    Learn more

Frequently asked questions

Are there any vacation home rentals in Panama City?
Book one of our 1,996 vacation home rentals and begin planning your trip to Panama City. Whether you’d like to stay in Gulf Coast Development, Bunkers Cove, Gwaltney Estate or another popular area, you’ll find the ideal house on Vrbo.
How much does it cost to stay in a vacation rental house in Panama City?
Your ideal vacation home rental in Panama City is only a few clicks away, with prices varying from wallet-conscious stays to more luxurious options. Enter your travel dates and then filter based on your preferences, ensuring you find the best place for you and your crew.
When is the best time to rent a vacation house in Panama City?
This can all depend on the weather conditions you prefer, along with other factors. Many people visiting Bay County stay in a Panama City vacation home rental in March, when the average temperature ranges from 57ºF (14ºC) to 69ºF (21ºC).
Where can I rent a Panama City vacation house with great views?
Book a vacation home rental in Panama City and you’ll be waking up to impressive vistas. Some of our more popular rental houses in this destination offer beach views.
Does Panama City have any weekend house rentals?
Some of Vrbo’s vacation houses are available for weekend rental, making them perfect for impromptu getaways. Enter your desired travel dates to check out the availability. You may need to adjust the dates and have a little flexibility in your travel plans to find the right vacation home rental in Panama City.
Are there any pet-friendly house rentals in Panama City?
Spend your next adventure with your four-legged friend at one of the 32 pet-friendly vacation home rentals in Panama City. These properties come with features that’ll make your pooch feel at home, such as a fenced-in yard. Just select the “Pets allowed” filter to book a house that has space for every precious member of your family.
What are the top things to do in Panama City?
Planning an unforgettable getaway to Panama City means finding fun things for all the family. St. Andrews State Park, Panama City Mall and Panama City Marina are just the start of the options here. And Vrbo’s vacation home rentals are a fabulous base for your sightseeing activities.
Why should I book my vacation rental house with Vrbo?
When you choose a Vrbo vacation home rental, the only people you have to share your living space with are the people you take with you. It’s only you, your closest companions and the whole property to yourselves. Plus, when you’re a member of our One Key™ rewards program, you can collect and redeem OneKeyCash™* on all eligible bookings on Vrbo, Expedia and Hotels.com. Additionally, our flexible cancellation policies also mean you can book your rental house with peace of mind if your plans change. *OneKeyCash disclaimer - OneKeyCash is not redeemable for cash and can only be used on Hotels.com, Expedia and Vrbo.

More Vacation Rentals ideas

People also search for