Big Pine Key house rentals

Opt for one of our 629 vacation home rentals in Big Pine Key and you’ll have the perfect base for your next great adventure. Sands, Whispering Pines and Atlantis Estates are among the city’s most sought-after neighborhoods.

Whether you’re searching for a budget-conscious getaway or an upscale retreat, Vrbo has a range of vacation home rentals in Big Pine Key to choose from. Use our filter tools to narrow down your options and find the perfect stay that meets your needs.

Use the “Location” filter to find a vacation home rental with the views you’re looking for. Start by entering the dates you want to book your house in Big Pine Key, then narrow your options based on the type of area you’d rather stay in.

Some of Vrbo’s vacation houses can be rented just for the weekend, making them perfect for impulsive getaways. Key in your desired travel dates to view the availability. You may need to adjust the dates and be flexible with your travel plans to find the right vacation home rental in Big Pine Key.

You bet. There are 17 vacation home rentals where pets are allowed in Big Pine Key, so your furry companion doesn’t have to miss out on the adventures. Use our filter tool to search for pet-friendly houses that feature perks like dog beds and complimentary treats for them, and plenty of cozy conveniences for you.

From Bahia Honda State Park to Calusa Beach and National Key Deer Refuge Visitor Center, there are plenty of exciting things to do and see during your family escape to Big Pine Key. With the sightseeing sorted out, we’re here to help you find a vacation home rental that fits your taste and budget.

No sharing your space, no awkward encounters with people you don’t know. When you stay in a Vrbo vacation home rental, you’ll get the whole place to yourself. Plus, thanks to our One Key™ rewards program, you can collect and spend OneKeyCash™* on all eligible bookings on Vrbo, Expedia and Hotels.com. Need to cancel or change your itinerary? Our flexible cancellation policies mean you can book your rental house with total peace of mind. *OneKeyCash disclaimer - OneKeyCash is not redeemable for cash and can only be used on Hotels.com, Expedia and Vrbo.