South San Francisco house rentals

Book one of our 955 vacation home rentals and start organizing your South San Francisco trip. Whether you’d like to be in Downtown South San Francisco, The East Side, Oyster Point or another well-known neighborhood, you’ll find the perfect house on Vrbo.

Discover a range of vacation home rentals in South San Francisco, where you’ll find prices to meet every preference. From budget-conscious choices to upmarket properties, Vrbo makes it a cinch to compare places to find the ultimate stay for your trip.

Consider visiting South San Francisco in May, when the average temperature is between 51ºF (11ºC) and 64ºF (18ºC). This is the most popular month for guests to get a vacation home rental in this destination, which is located in San Francisco.

Use the “Location” filter to find a vacation home rental with the views you’re looking for. Begin by entering the dates you want to book your house in South San Francisco, then narrow your options based on the sort of area you’d prefer to stay in.

You’ll discover some fabulous houses that are available for weekend rental. Simply enter your dates of travel and prepare for a spontaneous few days of fun. If you can’t find the ideal vacation home rental in South San Francisco straight away, just alter your dates and search again.

If you want to discover South San Francisco with your furry friend at your side, use our convenient filter tool to browse pet-friendly houses. Check the box marked “Pets allowed” to find a vacation home rental with perks like fenced-in yards and complimentary treats. Because when the family goes on vacation, the pets should be part of the fun!

There’s loads to do with you and your kids in South San Francisco besides enjoying the comforts and conveniences of your vacation home rental. Don’t miss top attractions like Pier 39 and Golden Gate Bridge. Want some more inspiration? Alcatraz Island deserves a spot on every South San Francisco sightseeing list.

Excellent customer support from the minute you book until after your stay is among several reasons to choose Vrbo for your upcoming vacation home rental. We also have properties that go beyond the usual hotel room — think houses in spectacular locations, whether that’s by the beach or along a lakeshore. Plus, with our One Key™ rewards program, you can earn and redeem OneKeyCash™* on eligible bookings with Vrbo, Expedia and Hotels.com. And with flexible cancellation policies and benefits like damage deposit protection, we make getting away easy. *OneKeyCash disclaimer - OneKeyCash is not redeemable for cash and can only be used on Hotels.com, Expedia and Vrbo.