Mesa house rentals

Pick from 5,059 vacation home rentals in Mesa that have more privacy, space, value and amenities compared to a standard hotel room. Search for houses in desirable areas such as West Second Street Historic District, Escobedo Historic District and Park Center Place.

Whether you’re searching for a budget-conscious getaway or a high-end retreat, we offer a range of vacation home rentals in Mesa for you to choose from. Use our filters to compare options and find the right place for you and your crew.

The majority of guests enjoy staying in a vacation home rental in Mesa during November. At this time of year, average temperatures range between 59ºF (15ºC) and 77ºF (25ºC) in this part of Phoenix.

At Vrbo, we have vacation home rentals with views that’ll make you want to press pause to soak it all in. To find houses in Mesa with epic vistas, enter your dates, then sort your search results by “Recommended” and “Guest rating” and see what pops up. Want to really immerse yourself in your picturesque surroundings? Browse for vacation homes with outdoor spaces or balconies.

Some of our vacation houses can be rented just for the weekend, making them ideal for last-minute getaways. Key in your preferred travel dates to view the availability. You may need to play around with dates and have a little flexibility in your plans to find the right vacation home rental in Mesa.

Spend your next adventure with your furry companion at one of the 51 pet-friendly vacation home rentals in Mesa. These properties come with features that’ll make your pup feel at home, including their own cozy bedding. Just check the “Pets allowed” filter to book a house that has room for every cherished member of your family.

It’s no surprise why many families love Mesa, with top-rated attractions like Camelback Mountain, Phoenix Zoo and Sun Devil Stadium to explore. Discover this destination’s best sights together and then return to the cozy comforts of your vacation home rental.

First-rate customer support from the second you book until after your stay is one of the many reasons to choose Vrbo for your vacation home rental. We also offer properties that go beyond the basic hotel room — think houses in spectacular locations, whether that’s by the beach or along a lakeshore. Plus, with our One Key™ rewards program, you’ll be able to earn and use OneKeyCash™* on eligible bookings with Vrbo, Expedia and Hotels.com. And with flexible cancellation policies and benefits like payment protection, we ensure peace of mind. *OneKeyCash disclaimer - OneKeyCash is not redeemable for cash and can only be used on Hotels.com, Expedia and Vrbo.